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¹ Central Fisheries Research Institute, Trabzon, Turkey DOI : 10.4194/2459-1831-v1_1_02 Viewed : 9615 - Downloaded : 3930 Antibiotic resistance and presence of the resistance genes were investigated in the Vancomycin Resistant Enterococci (VRE) isolated from sediment in cage areas. A total of 85 Enterococcus faecium strains were isolated from the sediment samples. The Minimum Inhibitory Concentration (MIC) tests were indicated that, 16.47% of the E. faecium strains resistant to vancomycin. Following the detection of antimicrobial susceptibilities of the isolates, occurrence of the vancomycin resistance genes (vanA, vanB, vanC1) were determined by PCR. At least one vancomycin resistance gene was found in 64.7% of the E. faecium strains. The vanA, vanB and vanC1 genes were determined in 29.41%, 31.76% and 25.88% of the bacteria respectively. These results indicate fish cage farming can play an important role in the development of antibiotic resistance among VRE. Keywords : Antimicrobial resistance, Enterococci, net cage, Turkey